If you’re looking for where to buy acetaminophen 325 mg over the counter in Australia, then our pharmacy is ready to provide you with the most favorable conditions for purchasing medicines with no prescription. Patients successfully use acetaminophen for the treatment of diseases explained in the manual below. Our online pharmacy provides fast delivery throughout Australia. Purchase and make sure of this high quality of our service. Since we sell absolutely all medications without a prescription, carefully read all the contraindications, side effects and interactions with other medications. In any case, we advise you to consult with your doctor.
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Acetaminophen is used to relieve mild to moderate pain from headaches, muscular aches, menstrual periods, colds and sore throats, toothaches, backaches, and responses to vaccinations (shots), and to decrease fever. Acetaminophen may also be used to alleviate the pain of osteoarthritis (arthritis caused by the breakdown of the lining of the joints). Acetaminophen is in a class of drugs called analgesics (pain relievers) and antipyretics (fever reducers).
It works by cooling your system and from altering how in which the body feels pain.
Side Effects
Toxity
Oral, mouse: LD50 = 338 mg/kg; Oral, rat: LD50 = 1944 mg/kg. Acetaminophen is metabolized primarily in the liver, in which a lot of it is converted to inactive compounds by conjugation with glucuronic acid and, to a lesser extent, sulfuric acid. Conjugates are subsequently excreted from the kidneys. Just a small part is excreted in unchanged in urine or oxidized through the hepatic cytochrome P450 enzyme system (CYP2E1). Metabolism via CYP2E1 creates a toxic metabolite, N-acetyl-p-benzoquinoneimine (NAPQI). The poisonous effects of acetaminophen are because of NAPQI, maybe not acetaminophen itself nor some of the main metabolites. At therapeutic dosages, NAPQI reacts with the sulfhydryl group of glutathione to generate a non-toxic conjugate that’s excreted by the kidneys. High levels of acetaminophen can cause glutathione depletion, accumulation of NAPQI and hepatic necrosis. The maximum daily dose of acetaminophen is 4 g. Liver failure was seen at doses as low as 6 grams every day. Therefore, the maximum daily and only dose of acetaminophen is presently being examined in a few nations. N-acetyl-cysteine, a precursor of glutathione, could be administered in case of acetaminophen toxicity.
Acetaminophen Interactions
Inform your doctor about all the medications that you take, including non-prescription and prescription drugs, vitamins, and herbal nutritional supplements. Especially tell your health care provider if you choose:
- Anticoagulants (‘blood thinners’) such as warfarin (Coumadin, Jantoven)
- isoniazid (INH)
- particular drugs for seizures such as carbamazepine (Tegretol), phenobarbital, and phenytoin (Dilantin)
- medicines for fever, fever, coughs, and colds
- medicines for mental sickness and nausea like chlorpromazine, thioridazine, perphenazine, and prochlorperazine (Compro, Procomp)
This isn’t an entire collection of all acetaminophen drug interactions. Consult your physician or pharmacist to find out more.