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Alfacalcidol 0.25 Mcg
Alfacalcidol is a active metabolite of Vitamin D, which performs roles that are important in regulation of the bone metabolism and their calcium balance. Alfacalcidol is vitamin D-hormone analog that’s triggered by the from the liver for systemic and at osteoblasts for actions that are neighborhood. It possesses a exceptional pattern of pleiotropic effects on, e.g.
intestine, bone, pararthyroids, muscle and mind. Alfacalcidol is superior to plain vitamin D (cholecalciferol) because the last kidney activation of the latter is controlled by a negative feedback mechanism.
Hypercalcemia — Early signs of hypercalcemia, include nausea and vomiting, weakness, headache, somnolence, dry mouth, constipation, metallic taste, muscular soreness and bone pain. Late signs and signs of hypercalcemia, include polyuria, polydipsia, anorexia, weight loss, nocturia, conjunctivitis, pancreatitis, photophobia, rhinorrhea, pruritis, hyperthermia, decreased libido, elevated BUN, albuminuria, hypercholesterolemia, elevated ALT (SGPT) and AST (SGOT), ectopic calcification, nephrocalcinosis, hypertension and cardiac arrhythmias.