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Amiodarone Hydrochloride 100 Mg
Cordarone, Nexterone, Pacerone
Amiodarone is used to treat and prevent certain forms of severe, life-threatening ventricular arrhythmias (a particular kind of abnormal heart rhythm if other medicines did not assist or couldn’t be tolerated. Amiodarone is in a class of medications. It works by relaxing heart muscles that are overactive.
Side Effects
- thyroid problems. Amiodarone can cause thyroid problems, including low thyroid function or overactive thyroid function. Your doctor may arrange regular blood tests to check your thyroid function during treatment with amiodarone. Call your doctor if you have weakness, weight loss or weight gain, heat or cold intolerance, hair thinning, sweating, changes in your menses, swelling of your neck (goiter), nervousness, irritability, restlessness, decreased concentration, depression in the elderly, or tremor.
- skin problems. Amiodarone can cause your skin to be more sensitive to the sun or to turn a bluish-gray color. In most patients, skin color slowly returns to normal after stopping amiodarone. In some patients, skin color does not return to normal.
- nerve problems. Amiodarone can cause a feeling of “pins and needles” or numbness in the hands, legs, or feet, muscle weakness, uncontrolled movements, poor coordination, and trouble walking.
- vision problems that may lead to permanent blindness. You should have regular eye exams before and during treatment with amiodarone. Call your doctor if you have blurred vision, see halos, or your eyes become sensitive to light.
Toxity
Intravenous, mouse: LD50 = 178 mg/kg. Some unwanted effects have a substantial mortality rate: namely, hepatitis, exacerbation of asthma and congestive failure, and pneumonitis.
Amiodarone Interactions
Inform your doctor about all the medications you take including prescription and nonprescription medications, vitamins and herbal nutritional supplements. Amiodarone and certain other medications may interact with each other causing serious side effects. At times the dosage of amiodarone or alternative drugs have to be altered when they’re used jointly. Particularly, tell your physician if you’re taking:
- Antibiotic drugs used to treat diseases
- depression drugs
- blood inflammatory medications
- HIV or AIDS drugs
- cimetidine (Tagamet), a medication for stomach ulcer or ulcer
- loratadine (like: Claritin, Alavert), also a medication for allergy symptoms
- prescription drugs
- diabetes drugs
- cyclosporine, an immunosuppressive medicine
- dextromethorphan, a cough medication
- medicines to the heart, blood circulation, or blood pressure
- Water tablets (diuretics)
- hypertension or bile medicines
- narcotic pain drugs
- St. John’s Wort
Know the medicines you require. Maintain a record of these with you in all times and show it to your physician and pharmacist every time you receive a new medication. Don’t take any drugs while you are taking amiodarone if you don’t have spoken with your health care provider.