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Clozapine is used to treat the symptoms of schizophrenia (a mental illness that causes disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions) in individuals who have never been assisted by other medicines or who have attempted to kill themselves and therefore are very likely to attempt and kill or hurt themselves again. Clozapine is in a class of drugs called atypical antipsychotics.
It works by altering certain substances in the brain’s action.
Side Effects
- low blood pressure
- sedation
- tremor
- syncope (fainting or “passing out”)
- dry mouth
- visual disturbances
- nausea
- dizziness/vertigo
- tachycardia (fast heartbeat)
- fever
- headache
- hypersalivation
- constipation
- sweating
Toxity
Clozapine conveys a black-box warning for agranulocytosis.