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Diphenhydramine can be used to relieve itchy, itchy, and watery eyes; coughing; and runny nose caused by allergies hay fever, or even the frequent cold. Diphenhydramine can also be used to alleviate nausea caused by throat or airway irritation. Diphenhydramine can also be used to prevent and treat motion sickness, also to deal with insomnia (trouble falling asleep or staying asleep).
Diphenhydramine can also be used to control abnormal movements in those who have early phase parkinsonian syndrome (a disease of the nervous system which causes problems with movement, muscle control, and equilibrium) or who are having movement issues because a side effect of a drug.
The symptoms of those ailments will alleviate but won’t deal with the cause of the signs or accelerate recovery. Diphenhydramine shouldn’t be used to cause sleepiness.
Diphenhydramine is in a class of drugs called antihistamines. It works by blocking the actions of histamine, a chemical in the body that causes allergic symptoms.
Toxity
LD50=500 mg/kg (orally in rats). Substantial overdosage may result in myocardial infarction (heart attack), severe hepatitis dysrhythmias, coma and death.