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Zetia
Ezetimibe can be used jointly with lifestyle changes (diet, weight loss, exercise) to decrease the amount of cholesterol (a fat-like material) and other fatty substances from the bloodstream. It could be used by itself or in conjunction with an HMG-CoA reductase inhibitor (statin). Ezetimibe is in a class of drugs called drugs. By preventing the absorption of cholesterol from the 11, it works.
Buildup of cholesterol and fats along the walls of these arteries (a process called atherosclerosis) decreases blood circulation, which reduces the oxygen supply to your heart, brain, and other areas of the human body.
Lowering blood levels of cholesterol and fats may help decrease this buildup and might reduce your odds of developing heart conditions like angina (chest pain), strokes, and heart ailments. Results of a clinical study which compared people who obtained ezetimibe and simvastatin with individuals who took simvastatin lately discovered that although the band of folks taking ezetimibe and simvastatin had reduced levels of cholesterol from the bloodstream, there was no gap between the 2 groups at the total amount of cholesterol and cholesterol buildup on the interiors of the arteries in the throat.
The lowering of cholesterol levels in the bloodstream didn’t lead in people it isn’t currently known. Studies are underway to evaluate therapy with simvastatin and ezetimibe with simvastatin to therapy whether there’s a gap in the probability of cardiovascular disease, to see. Talk regarding advantages and the risks of treating levels of cholesterol with medicines in your bloodstream.
Making changes can decrease your blood cholesterol levels, along with choosing a medicine.
You need to eat a diet that’s low in saturated fat and cholesterol (see SPECIAL DIETARY); exercise thirty minutes in most, if not all, days; and get rid of weight if you’re overweight.
Side Effects
- If you experience unexplained muscle pain, tenderness, or weakness while taking ezetimibe, contact your doctor immediately.
- depression
- joint pain
- stomach pain
- alterations in some laboratory blood tests
- liver problems
- Patients have experienced severe muscle problems while taking ezetimibe, usually when ezetimibe was added to a statin drug.
- inflammation of the pancreas
- allergic reactions (which may require treatment right away) including swelling of the face, lips, tongue, and/or throat that may cause difficulty in breathing or swallowing,
- You need to do this promptly, because on rare occasions, these muscle problems can be serious, with muscle breakdown resulting in kidney damage.
- muscle aches
- gallstones
- nausea
- In clinical studies patients reported few side effects while taking ezetimibe. These included diarrhea, joint pains, upper airway infection, and feeling tired.
- dizziness
- inflammation of the gallbladder
- headache
- raised red rash, sometimes with target-shaped lesions
- rash, and hives
- tingling sensation
Toxity
The most frequent adverse reactions from the number of patients treated with ezetimibe that resulted in treatment discontinuation and occurred at a rate greater than placebo were, arthralgia (0.3 percent), nausea (0.2 percent), along with gamma-glutamyltransferase growth (0.2 percent).
Ezetimibe Interactions
Inform your doctor about all the medications you take including non-prescription and prescription drugs, vitamins, and herbal nutritional supplements. Especially tell your health care provider if you choose:
- cyclosporine (Neoral, Sandimmune)
- gemfibrozil (Lopid)
- fenofibrate (Tricor, Fibricor)
- cholestyramine (Questran, WellChol, Colestid)
- warfarin (Coumadin)
This isn’t an entire collection of all ezetimibe drug interactions. Ask your physician to find out more.