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Viramune, Viramune XR
Nevirapine is used alongside other drugs to treat human immunodeficiency virus (HIV) disease in adults and children 15 days old and older. Nevirapine shouldn’t be used when treating other people or health workers exposed with body fluids, tissues, or blood after contact. Nevirapine is in a class of drugs called non-nucleoside reverse transcriptase inhibitors (NNRTIs).
It works by lowering the quantity of HIV in the blood. Although nevirapine doesn’t cure HIV, it might decrease your odds of developing acquired immunodeficiency syndrome (AIDS) and HIV-related disorders like severe infections or cancer. Taking these drugs together with practicing safer sex and creating other lifestyle changes can reduce the chance of transmitting (dispersing) that the HIV virus into other men and women.
Side Effects
- Changes in your immune system (Immune Reconstitution Syndrome) can happen when you start taking HIV medicines. Your immune system may get stronger and begin to fight infections that have been hidden in your body for a long time. Tell your doctor if you start having new symptoms after starting your HIV medicine.
- Changes in body fat can happen in some people who take antiretroviral therapy. These changes may include increased amount of fat in the upper back and neck (“buffalo hump”), breast, and around the middle of your body (trunk). Loss of fat from your legs, arms, and face can also happen. The cause and long-term health effects of these problems are not known at this time.
- See “Nevirapine Precautions”.
Toxity
Signs of overdose include edema, erythema nodosum, fatigue, fever, headache, sleeplessness, nausea, pulmonaryinfiltrates, rash, vertigo, nausea, and weight reduction. The most frequent adverse reaction is rash.
Nevirapine Interactions
Tell your doctor and pharmacist about all the medications that you take, including non-prescription and prescription drugs, vitamins and herbal nutritional supplements. Nevirapine may influence the way other medicines work, and other drugs may affect how nevirapine functions.
You shouldn’t take nevirapine in the event you also choose:
- St. John’s Wort. St. John’s Wort can diminish the sum of nevirapine within your system.
- efavirenz (Sustiva, Atripla). Efavirenz may allow you to have an increased chance of unwanted effects.
- Atazanavir (Reyataz)
- boceprevir (Victrelis)
- telaprevir (Incivek)
- lopinavir and ritonavir (Kaletra)
- fosamprenavir calcium (Lexiva)
- itraconazole (Sporanox)
- ketoconazole (Nizoral)
- rifampin (Rifadin, Rifamate, Rifater)
- Birth control Pills. Birth control pills taken by mouth (oral contraceptives) and additional hormone kinds of birth control might not work to avoid pregnancy. Talk to your physician about other kinds of birth control which you can use to avoid pregnancy during therapy with nevirapine.
Also tell your health care provider if you choose:
- clarithromycin (Biaxin)
- fluconazole (Diflucan)
- indinavir sulfate (Crixivan)
- methadone
- nelfinavir mesylate (Viracept)
- rifabutin (Mycobutin)
- warfarin (Coumadin, Jantoven)
- saquinavir mesylate (Invirase)
If you aren’t positive whether you choose a medication previously, ask your health care provider or pharmacist.Know the drugs you require. Maintain a record of these to demonstrate your physician or pharmacist in case you receive a new medication.