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Pamelor
Nortriptyline is used as a treatment for depression. Nortriptyline is in a group of drugs called antidepressants. It works by increasing the amounts of certain all-natural substances in the mind which are required to maintain balance.
Side Effects
- drowsiness
- nausea
- difficulty urinating
- nightmares
- weight gain
- dry mouth
- changes in sex drive
- constipation
- weakness
- headache
- dizziness
- blurred vision
- changes in heart rhythm
- increased sweating
Toxity
Signs of overdose include cardiac dysrhythmias, severe hypotension, shock, congestive heart failure, pulmonary edema, convulsions, and CNS depression, including coma. Changes in the electrocardiogram, particularly in QRS axis or width, are clinically significant indicators of tricyclic antidepressant toxicity.
Side effects include: sedation, hypotension, blurred vision, dry mouth, constipation, urinary retention, postural hypotension, tachycardia, hypertension, ECG changes, heart failure, diminished memory and delirium, and precipitation of hypomanic or manic episodes in bipolar depression.
Withdrawal symptoms include gastrointestinal disturbances, nervousness, and sleeplessness.
Nortriptyline Interactions
Inform your doctor about all the medications that you take, including non-prescription and prescription drugs, vitamins, and herbal nutritional supplements.
Especially tell your health care provider if you choose:
- Drugs which use the enzyme CYP2D6 like desipramine, dextromethorphan, atomoxetine, quinidine, propafenone and flecainide
- drugs that prevent a protein from the system (CYP2D6) like quinidine (Qualaquin), fluoxetine (Prozac, Sarafem), amitriptyline (Elavil, Amitril, Amitid), and paroxetine (Paxil)
- cimetidine (Tagamet)
- reserpine
- selective serotonin reuptake inhibitors (SSRIs) such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil), and sertraline (Zoloft)
- MAOI’s like isocarboxazid (Marplan), phenelzine (Nardil), tranylcypromine (Parnate), and selegiline (Emsam, Eldepryl, Zelapar), rasagiline (Azilect)
- linezolid (Zyvox)
- triptans
- fentanyl
- lithium
- tramadol
- tryptophan
- buspirone
- St. John’s Wort
Your physician might have to change the doses of your medications or monitor you carefully for side effects.
This isn’t an entire collection of all nortriptyline drug interactions. Consult your physician or pharmacist to learn more.