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Stavudine 30 Mg
Zerit
Stavudine is used alongside other drugs to treat human immunodeficiency virus (HIV) disease. Stavudine is in a class of drugs called nucleoside reverse transcriptase inhibitors (NRTIs). It works by lowering the quantity of HIV in the blood. Though stavudine doesn’t cure HIV, it might decrease your odds of developing acquired immunodeficiency syndrome (AIDS) and HIV-related disorders like severe infections or cancer.
Taking these drugs together with practicing safer sex and creating other lifestyle changes can reduce the chance of transmitting (dispersing) that the HIV virus into other individuals.
Side Effects
- upper back and neck (buffalo hump)
- headache
- diarrhea
- weakness in your legs, feet, arms, or hands
- Stavudine can cause lactic acidosis, liver problems, and pancreatitis. See “Drug Precautions”.
- Neurologic symptoms. Symptoms include: weakness of your legs, feet, arms, or hands (motor weakness) and numbness or tingling in your hands or feet (neuropathy). These problems can happen more often in people who have advanced HIV disease, have a history of peripheral neuropathy, or in people who take other medicines that also are associated with neuropathy including didanosine. In some cases, neuropathy may temporarily worsen after you stop taking stavudine. Neuropathy can be difficult to notice in children who take stavudine. Ask your child’s healthcare provider for the signs and symptoms of peripheral neuropathy in children.
- It is important to call your healthcare provider right away if you have:
- numbness in your hands or feet
- arms
- Changes in your immune system (immune reconstitution syndrome). Your immune system may begin to fight infections that have been in your body for a long time. Tell your healthcare provider if you start having new or worse symptoms of infection after you start taking HIV medicine.
- tingling in your hands or feet
- nausea
- face
- rash
- more fat in or around your
- trunk
- vomiting
- breast or chest
- loss of fat in your
- legs
- These changes may include:
- Changes in body fat (fat redistribution). Changes in body fat (lipoatrophy or lipodystrophy) have been seen in some people taking HIV medicines including stavudine. Loss of body fat (lipoatrophy) happens more often in people who take stavudine than in people who take other similar HIV medicines.
Toxity
Side effects include peripheral neuropathy tingling, tingling, tingling, or pain at the feet or hands), fatal lactic acidosis has been reported in patients treated with stavudine (ZERIT) in conjunction with other antiretroviral agents, severe liver enlargement, inflammation (swelling and pain) of the liver, and liver failure.
Stavudine Interactions
Inform your health care provider about all of the medications that you take, including non-prescription and prescription drugs, vitamins, or herbal nutritional supplements. Stavudine may influence the way other medicines work, and other medications may affect how stavudine functions.
Especially tell your health care provider if you choose:
- Combivir, Retrovir, Trizivir (zidovudine or AZT)
- Videx or Videx EC (didanosine)
- Adriamycin, Rubex (doxorubicin)
- Copegus, Rebetol, Ribasphere, Ribavirin, Virazole (ribavirin)
- Roferon-A, Intron-A many others (interferon)
- Hydrea, Droxia (hydroxyurea)
Know the medicines you require. Maintain a record of the medications and reveal it to your health care provider and pharmacist if you receive a new medication.
Consult your health care provider if you aren’t certain whether you take just one of these medications listed above.
Efek Samping Obat HIV (ARV) Zidovudine(AZT), Lamuvudine(3TC) dan Stavudine(d4T), Dr. Teguh Haryono
- It is important to call your healthcare provider right away if you have: