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Qudexy XR, Topamax, Topiragen, Trokendi
Topiramate is used by itself or with other drugs to treat specific kinds of seizures such as main generalized tonic-clonic seizures (previously called a grand mal seizure; pus which involves the whole body) and partial onset seizures (seizures that involve just 1 portion of their mind). Topiramate can also be used with other drugs to control seizures in those who have Lennox-Gastaut syndrome (a disease that causes seizures and developmental delays). Topiramate is used to prevent migraine headaches whenever they happen.
Topiramate is in a class of medications. It works by decreasing abnormal excitement in the brain.
Side Effects
- Metabolic acidosis. Metabolic acidosis can cause:
- tiredness
- a change in the way foods taste
- Effects on thinking and alertness. Topiramate may affect how you think and cause confusion, problems with concentration, attention, memory, or speech. Topiramate may cause depression or mood problems, tiredness, and sleepiness.
- Dizziness or loss of muscle coordination.
- diarrhea
- nausea
- upper respiratory tract infection
- Kidney stones. Drink plenty of fluids when taking topiramate to decrease your chances of getting kidney stones.
- High blood ammonia levels. High ammonia in the blood can affect your mental activities, slow your alertness, make you feel tired, or cause vomiting. This has happened when topiramate is taken with a medicine called valproic acid (Depakene and Depakote).
- impaired consciousness
- not feeling hungry
- tingling of the arms and legs (paresthesia)
- nervousness
- irregular heartbeat
- Low body temperature. Taking topiramate when you are also taking valproic acid can cause a drop in body temperature to less than 95В°F, feeling tired, confusion, or coma.
- loss of appetite
- weight loss
Toxity
Signs of overdose include abdominal pain, stiffness, blurred vision, convulsions, depression, nausea, double vision, nausea, impaired coordination, diminished mental activity, very low blood pressure, decreased consciousness, acute nausea, sluggishness, and address issues.
Topiramate Interactions
Inform your doctor about all the medications you take including non-prescription and prescription drugs, vitamins, and herbal nutritional supplements. Especially tell your health care provider if you choose:
- Other drugs for epilepsy (phenytoin, carbamazepine, and valproic acid)
- birth control drugs taken by mouth (oral contraceptives)
- metformin
- lithium
- additional carbonic anydrase inhibitors (zonisamide, acetazolamide, dichlorphenamide)
- CNS depressants (drugs that encircle your thinking, concentration or muscle operation). For instance:
- drugs for anxiety
- medicines for sleeplessness
- pain drugs
- alcohol
This isn’t an entire collection of potential drug interactions using topiramate. Talk with your health care provider or pharmacist to find out more.
Medication Update: Topiramate #2